Description
Product Characteristics: FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. SUBCELLULAR LOCATION: Cell junction âÄ° synapse âÄ° postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein. Tissue specificity: Highly expressed in the retina and in a lesser extent in brain, lung and thymus.,GABA Receptors,GABRR1, GABA(C) receptor
Target Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]